The Edward E. Marsh Ephemera Collection is largely comprised of over 30 loose-leaf, matching leather binders of collected ephemera, pulps, magazines, art, and manuscripts from key figures in the development of the science fiction and pop culture, including Forrest J. Ackerman, Robert Heinlein, Frank Herbert, Ray Bradbury, Isaac Asimov, and Jules Verne. The collection also contains original artwork from prominent science fiction illustrators such as Kelly Freas, Frank Frazetta, and Gerry Grace as well as sculptural works by Anne Fewell. Original limited ephemera from both film and literary works: Battlefield Earth, Dune, and Blade Runner are also included.

The collection is divided into nine series: Edward E. Marsh Golden Age of Science Fiction Library Binders, Ephemera Enclosures, Edward E. Marsh Author Library Binders, Edward E. Marsh Artist Library Binders, Original Artwork, Sculptural Works, Film Memorabilia and Collectibles, Artifacts, and Awards.

The Edward E. Marsh Golden Age of Science Fiction Library Binders are arranged alphabetically by author name with binder contents described at the item level and notes signed and limited edition copies. The binders highlight prominent Golden Age of Science Fiction authors and include serials and magazines, fanzine clippings, original manuscripts, photographs, and personal ephemera. Authors include Forrest J. Ackerman, Isaac Asimov, Ray Bradbury, Will Durant, Robert Heinlein, Frank Herbert, and Jules Verne.

The Book Ephemera consists of various loose serials, news clippings, photographs, and other ephemera found in books within the Marsh Library. The items were removed from the cataloged monographs and arranged into a separate subseries.

The Edward E. Marsh Author Library Binders include materials collected in two subseries documenting Winston S. Churchill's writing, Prime Minister of the United Kingdom from 1940-1945 and 1951-1955; and Ernest Hemingway's Old Man and the Sea. The Churchill items are biographical magazine articles and a binder from the Centenary Trust medals. The Old Man and the Sea subseries contains promotional materials related to the published book as well as the film adaptation.

The Edward E. Marsh Artist Library Binders contain artwork by science fiction illustrator Kelly Freas and others. The binders represent original pen and pencil sketch drawings, lithographic prints, and published magazine covers. The majority of the art is signed by Kelly Freas.

The Original Artwork series is arranged in three subseries: Portrait Paintings, Framed Artworks, and Oversize Prints. The portrait paintings were commissioned works of prominent science fiction and fantasy authors, including many in the Marsh Library. The acrylic on canvas works were painted by Los Angeles artist, Anne Fewell and Judah Dobin.

The framed artworks are limited edition prints and off-set lithographs by well-known science fiction and fantasy artists as Frank Frazetta, Gerry Grace, Charles Wildbank, and Greg Winters. A large selection of the work are print rendition illustrations for L. Ron Hubbard's Battlefield Earth.

The oversize prints are unframed large format lithographs and prints by well-known science fiction illustration as Frank Frazetta, Gerry Grace, Shun Kijima, Gary Meyer, and Charles Wildbank. Many of the prints are exclusive and limited edition illustrations for Battlefield Earth and Mission Earth.

The Sculptural Works series is arranged in two subseries: Portrait Busts and Published Books and Film Related.

The portrait busts are both life-size and small format original cast sculpture bust of prominent science fiction and fantasy authors in the Marsh Library. Many of the busts are cast bronze pieces and rendered by Los Angeles artist Anne Fewell. Also included are commissioned life-size portraits of Edward E. Marsh and L. Ron Hubbard. Unique pieces include a life mask of Forrest J. Ackerman and a marble resin bust of Robert Heinlein.

The other sculptural works are items from Battlefield Earth, including a bronze cast sculpture rendered after Frank Frazetta's illustration, "Man the Endangered Species".

Included in the Film Memorabilia and Collectibles series are ffive subseries: Battlefield Earth, Bladerunner, Dune, Miscellaneous, and The Edward E. Marsh Library Film Binders. Materials in these subseries include action figures, film props, and promotional materials related to the films. The film binders contain pictures, scripts, promotional matierials, DVDs, and soundtracks of a variety of films.

The subseries incorporates a wide range of objects and collectible material from well-known science fiction films. The items are unique and range from replica film props, limited edition toys and games, and paper ephemera. Unique items include film prop knives used in Dune and an over life-size costume character statue of Terl from Battlefield Earth.

The Artifacts series contains items from prominent science fiction authors, including the leather briefcase of Will Durant and various E-meters conceptualized and manufactured by L. Ron Hubbard. E-meters are devices that record human electrodermal activity and are used extensively in the Church of Scientology.

The Awards series contains the Dissemination Edition bronze statue from the Printing Industries of America award presented to Edward E. Marsh, as well as awards presented to Forrest J Ackerman and Henry Mancini.

The Exhibits and Conventions series includes programs and guides from San Diego Comic Con and other conventions.

The series of Catalogues and Bibliographies includes catalogues from small bookstores across the United States, catalogues of major sales, and fan and bookstore directories.

The Audiovisual Materials series includes casettes and CDs of science fiction audiobooks, lectures, and radio shows, DVDs of science fiction movies and television shows, 35 mm slides showcasing the covers of science fiction magazines from 1909-1976, and vinyl records primarily of recordings of the music of Henry Mancini.